It is one of the least edifying facts of recent American medical
history that the profession's leadership so long rejected as
quackish the idea that nutrition affects health (JAMA 1946 1949,
1977; Shimkin, 1976). Ignoring both the empirical dietary wisdom
that pervaded western medicine from the pre-Christian Hippocratic
era until the late nineteenth century and a persuasive body of
modern research in nutritional biochemistry, the politically
minded spokesmen of organized medicine in the U.S. remained long
committed to surgery and radiation as the sole acceptable
treatments for cancer. This commitment persisted, even after sound
epidemiological data showed that early detection and removal of
malignant tumors did not "cure" most kinds of cancer (Crile, 1956;
updated by Cairns, 1985).
The historical record shows that progress lagged especially in
cancer immunotherapy - including nutrition and hyperthermia -
because power over professional affiliation and publication (and
hence over practice and research) rested with men who were neither
scholars nor practitioners nor researchers themselves, and who
were often unequipped to grasp the rapidly evolving complexities
of the sciences underlying mid-twentieth-century medicine.
Nowhere is this maladaption of professional structure to
medicine's changing scientific context more tragically illustrated
than in the American experience of Max B. Gerson (1881- 1959),
founder of the best-known nutritional treatment for cancer of the
pre-macrobiotic era. A scholar's scholar and a superlative
observer of clinical phenomena, Gerson was a product of the German
medical education which Americans in the late 19th and early 20th
centuries considered so superior to our own that all who could
afford it went to Germany to perfect their training (Bonner,
1963). As a medical graduate of the University of Freiburg in
1909, Gerson imbibed all of the latest in scientific medicine,
with the emphasis on specificity which bacteriology had brought
into western medical thought in the preceding decades. Gerson
subsequently worked with leading German specialists in internal
medicine, in physiological chemistry, and in neurology (U.S.
Congress, 1946, 98). The historical record does not tell us
whether his medical education in Germany (where much of the early
work in nutritional chemistry took place) included a study of
diet, a subject neglected in American medical schools after the
germ theory gained acceptance.
We do know that by 1919, when Gerson set up a practice in internal
and nervous diseases in Bielefeld, he had devised an effective
dietary treatment for the migraine headaches which frequently
disabled him, despite the best efforts of his colleagues. In 1920,
while treating migraine patients by this salt-free vegetarian
diet, he discovered that it was also effective in lupus vulgaris
(tuberculosis of the skin, then considered incurable) and, later,
in arthritis as well (U.S. Congress, 1946, 98).
Trained in the theories of specific disease causation and
treatment that began to dominate western medicine - for the first
time in history - as bacteriological discoveries multiplied in the
late nineteenth century, Gerson was at first uneasy about using a
single therapy in such seemingly disparate conditions. But he was
committed to the primacy of clinical evidence, which he liked to
express in Kussmaul's dictum: "The result at the sick-bed is
decisive" (quoted in Gerson, 1958, 212). In later years, after
research began to provide explanations for Gerson's clinical
observations, he quoted Churchill on the mistaken course of action
he had thus avoided: "Men occasionally stumble over the truth, but
most pick themselves up and hurry off as if nothing had happened"
(Gerson, 1958, 212). Gerson persisted. In 1924 his success in
treating tuberculosis of the skin brought an invitation from the
noted thoracic surgeon, Ferdinand Sauerbruch, to test Gerson's
diet in a special lupus clinic to be provided by the Bavarian
government at the University of Munich. As Sauerbruch recounts it
in his autobiography, 446 patients out of 450 recovered - once he
had discovered and put an end to the smuggling of sausages, cream
and beer to the patients in the late afternoons ( Sauerbruch,
1953, 167- 171 ). Later extended to pulmonary tuberculosis as
well, this Gerson-Sauerbruch-Hermannsdorfer diet was widely used
in Germany and became the subject of Gerson's first book in 1934 (Gerson,
1934; Hildenbrand, 1987 communication).
During the late twenties and early thirties Gerson had several
experiences which informed his later thinking on diet and
degenerative disease. As a member of the State Board of Health,
appointed by the Prussian government, he was given extraordinary
laboratory support for a clinical trial of diet in pulmonary
tuberculosis. Besides the physiological parameters customarily
monitored in such work, Gerson was able to track minute
fluctuations in the patients' mineral metabolism and also in the
chemical composition of the foods he prescribed (Gerson, 1958,
183). At this same period he served as consultant to the Prussian
Ministry of Health on the best ways to restore to agricultural
usefulness the exhausted soil around several major German cities (Gerson,
1958, 183). When he learned that modern farming methods often rob
plant foods of their natural mineral and vitamin riches, while
increasing their sodium content, he began to think of the earth's
well-being as central to our own. Eventually he began to refer to
the soil, which nourishes the food we eat, as our "external
metabolism" (Gerson 1958, 175).
It was in 1928 that Gerson first used his diet in cancer, at the
insistence of a woman who had jaundice, high fever and two small
liver metastases after unsuccessful surgery for cancer of the bile
duct (Gerson, 1958, 31). On the strength of reports she had heard
of Gerson's work with tuberculosis, this woman insisted that he
write out a diet for the treatment of her cancer. Gerson
reluctantly agreed - after he obtained her signed statement that
she would not hold him responsible for the outcome! As he recalled
it many years later, this same patient had him read aloud to her a
chapter called "The Healing of Cancer" from a big book of about
1200 pages on folk medicine, " edited by three schoolteachers and
one physician, none of them practitioners. It was from this source
that Gerson first learned of the special soup which Hippocrates
supposedly gave to cancer patients and which Gerson made a fixture
of his cancer Therapy (Gerson, 1958, 31, 403-404; Gerson, 1978,
449-450). Having taken up this challenge against his will, with no
hope of success, Gerson was astounded when his patient seemed
fully recovered within six months (Gerson, 1958, 405). In quick
succession he had the same good results with two patients with
inoperable stomach cancer, both referred by this first patient.
Late in life he continues to marvel at these apparent recoveries
under his diet treatment (Gerson, 1958, 404- 405). (These notable
histories, which Gerson recounted in some detail, have prompted
one recent researcher to suggest the possible involvement of
aldoslerone as the mechanism of mineral-corticoid sensitivity in
gastrointestinal tumors. See McCarty, 1981).
In Vienna, where he lived for a time after the rise of Hitler,
Gerson's treatment failed in all seven patients he attempted to
treat in this manner - a failure which, in later years, he
attributed to inadequate dietary provisions in the sanitarium
where he then worked (Gerson, 1958, 31-32, 405). In Paris, where
he lived in 1935-36, the diet produced good results in three out
of seven cases (Gerson, 1958, 32, 405; Gerson, 1978, 451),
inspiring him to pursue such treatment further after he emigrated
to the United States in 1938.
Gerson constantly sought explanations for his observations in the
scientific literature, where he read widely in several languages (Gerson,
1958). In 1954, in "Cancer, a Problem of Metabolism," he credited
J. Maisin (1923) and B. Fischer-Wasels (1929) with advancing
physiological explanations of general predisposition toward tumor
formation and abandoning the theory of cancer causation by local
irritation. For the next few decades (according to Gerson's
account of the evolution of cancer concepts) there was a tendency
to interpret cancer in terms of constitution and diathesis, as was
done with diabetes, gout and tuberculosis. It was Caspari
(Nutrition and Cancer, 1938) who turned to metabolic explanation
of the kind Gerson ultimately favored (Gerson, 1954, 1). He
devoted an entire chapter of his book to a review of efforts,
largely by German researchers, to alter metabolism by diet (Gerson,
1958, 89-104). He found special appeal in Otto Warburg, The
Metabolism of Tumors, (London, 1930), in G. von Bergmann's
Funktionelle Pathologie (Berlin, 1932), and in Frederick Hoffman's
massive compilation, Cancer and Diet (Baltimore, 1937). Gradually,
out of his bedside experience and his reading, he formed a unitary
theory of degenerative disease (including cancer) which rested on
one of the oldest and most pervasive concepts in the history of
medicine: the vis medicatrix naturae or healing power of nature (Neuburger,
1926 and 1944; Warner, 1978). Endlessly seeking out the latest
researches and theories in physiology, biochemistry, and -
increasingly - immunology, Gerson rapidly integrated these massive
bodies of new detail into the larger framework of what he called
"the physician within", that is, the natural powers of resistance,
which we today call the immune system.
Gerson believed that cancer changes the body's normal
sodium/potassium balance, already disturbed by modern diet. Thus
his therapy used foods low in sodium (no salt added), high in
potassium, and rich in vitamins A and C and oxidizing enzymes. He
excluded fats and dairy products for the first four to six weeks,
considering them dangerously burdensome to the digestion in the
extremely sick patients who usually came to him only after having
exhausted conventional measures. Above all it was essential for
patients to eliminate excess sodium, which Gerson believed
responsible for altering cellular electrochemistry in favor of
cancerous growth.
There is now a great deal of research suggesting possible
mechanisms for the efficacy of Gerson's high potassium/low sodium
diet. As he suspected and we now know, hypokalemia often
accompanies cancer of the colon, and alterations in electrical and
mineral states occur often in cancer patients (Newell, 1981, 87).
Cone has furnished experimental proof of a correlation between the
level of electrical potential across somatic cell membranes and
the intensity of mitotic activity (Cone, 1971 ), a finding
supported by Zs.-Nagy and his colleagues in studies so human
thyroid cancer (Zs. -Nagy, 1983) . Ling's association/induction
hypothesis is based on laboratory studies which show that damaged
cells partially return to their normal configuration in high
potassium/low sodium environments (Ling, 1943), perhaps explaining
the remarkable tissue repair which Gerson sometimes saw in his
formerly debilitated patients (Cope, 1978). Lai has suggested that
intracellular sodium and potassium levels may furnish the
mechanism for regulating cellular differentiation and
transformation (Lai, 1985) .
To supply active oxidation enzymes and potassium-rich minerals,
Gerson's patients drank hourly glasses of freshly prepared
vegetable and fruit juices. As early as 1933-34, while living in
Vienna, Gerson had begun giving injections of liver extract, as
another means of stimulating the patient's liver (Gerson, 1958, 31
-32). In later years he had patients drink two to three glasses
daily of the juice of calves' liver pressed with carrots. In
addition to beta-carotene/vitamin A, this would supply iron and
copper, both of which affect peripheral T cell functions and other
peripheral lymphocyte subpopulations (Keusch, 1983, 345- 347).
Although the AMA Council on Pharmacy and Chemistry labeled as a
"false notion" the idea that diet can affect cancer, recent
researchers have found that "nutritional status plays a critical
role in immunological defense mechanisms at a number of important
levels" (Keusch, 1983, 345) and that nutritional factors "can have
profound influences on ... the development and manifestations of
cancers" as well as other diseases (Good, 1982, 85). In "The
Cancerostatic Effect of Vegetarian Diets" ( 1983), Siguel
describes as the ideal way to strengthen bodily defenses against
neoplastic cells a diet similar to Gerson's: high in carbohydrates
and vegetables, low in protein.
Like von Bergmann, Gerson believed that "every defense and healing
power of the body depends on the capacity of the body to produce a
so-called 'allergic inflammation'"- a truth long recognized by
surgeons, but somehow forgotten by medicine during the heyday of
microbiology. To Gerson this capacity to produce inflammation was
"the decisive part of the body's 'weapon of healing power'" (Gerson,
1958, 127-28).
Noting that fluid from a normal inflammation metabolism kills
cancer cells, but that blood serum does not, von Bergmann
concluded that a cancer metabolism occurs when the body can no
longer produce this healing inflammatory reaction (Gerson, 1958,
120- 121 ). Gerson agreed, but in contrast to von Bergmann and
most of his contemporaries, Gerson believed it was often possible
for the physician to help restore the vital power of inflammation,
even in anergic patients with advanced cancer. If cancer was a
degenerative disease caused by the cumulative effect of inadequate
nutrition with foods grown in soils depleted by artificial
fertilizers and poisoned by toxic insecticides and herbicides,
doctors must respond by replenishing the entire human organism.
For a condition that represented an ultimate failure of
equilibrium in a poisoned metabolism, removal of tumors by surgery
or radiation was merely superficial, symptomatic treatment.
"Medicine," Gerson said, "must be able to adapt its therapeutic
methods to the damages of the processes of our modern
civilization" (Gerson, 1958, 199).
Gerson set about doing this by altering the basic diet he had used
earlier in other conditions. Through meticulous observation of his
patients in New York (where he passed state boards in 1939), he
perfected a regimen of detoxication and diet requiring a high
degree of compliance by the patient, heroic devotion by the
patient's family, and close attention and frequent adjustment by
the physician. His therapy aimed to detoxify the body and restore
its healing apparatus, especially the liver, the visceral nervous
system, and the reticulo-mesenchymal system.
Gerson first encountered the idea of detoxication in cancer in the
version of Hippocratic regimen which he read with his first cancer
patient in Bielefeld in 1928 (Gerson, 1958, 404). After losing
several cancer patients to hepatic coma rather than to direct
effects of the disease (Gerson, 1958, 191 ), he realized that "The
digestive tract is very much poisoned in cancer'. The liver and
pancreas failed to function: "nothing is active" (Gerson, 1958,
407). To stimulate the liver, he began to use coffee enemas, which
0.A. Meyer of Goettingen had found effective in opening the bile
ducts in animals and which American surgeons in that period were
using in acute adrenal insufficiency and in shock from
postoperative hemorrhage and bleeding peptic ulcer (Beeson, 1980,
90, 96; Rothstein, 1987, 124). As he watched the progress of his
patients, he found that he could accelerate detoxication by giving
coffee enemas more frequently, with the addition of castor oil, by
mouth and by rectum (Gerson, 1958, 81).
Although Gerson used caffeine enemas primarily to facilitate
excretion of toxic wastes, especially from necrosing tumors, we
now realize that these enemas also promoted the absorption of
vitamin A, a process requiring the action of bile acids (Simone,
1943, 64). Thus the enemas that brought ridicule from Gerson's
enemies actually enabled his patients to use the enormous amounts
of vitamin A which his diet provided (recently estimated at about
100,000 IU daily: see Seifter, 1988). Vitamin A, in turn, plays a
vital role in immune function, perhaps by causing the helper cells
to induce the production of interleukin-2, or by causing killer
cell precursors to activate cytotoxic mechanisms, or by causing
suppressor T cells to eliminate down regulation (Keusch, 1983,
330-331 ).
Gerson also found that caffeine enemas greatly reduce pain, a
particular boon in his regimen, which avoids the use of opiates
and other painkilling drugs that might overtax the liver at a time
when its limited capacity is needed for immune functions and for
eliminating the toxic products of tumor breakdown.
Although the AMA Council on Pharmacy and Chemistry labeled as a
"false notion" the idea that diet can affect cancer, recent
researchers have found that "nutritional status plays a critical
role in immunological defense mechanisms at a number of important
levels" (Keusch, 1983, 345) and that nutritional factors "can have
profound influences on ... the development and manifestations of
cancers" as well as other diseases (Good, 1982, 85). In "The
Cancerostatic Effect of Vegetarian Diets" ( 1983), Siguel
describes as the ideal way to strengthen bodily defenses against
neoplastic cells a diet similar to Gerson's: high in carbohydrates
and vegetables, low in protein.
Gerson gradually added a few medications to his diet. One of these
was niacin, which he believed would help restore proper
intracellular potential, raise depleted liver stores of glycogen
and potassium, and aid in protein metabolism (Gerson, 1958, 32,
99- 100, 209). Another was iodine, which Gerson initially used
only in cases of low metabolic rates. When he found that "The best
range of healing power" was a BMR of +6 to +8 (monitored by
organic iodine in blood serum), and that iodine seemed to
counteract the neoplastic effect of hormones, he incorporated
iodine into the basic regimen, at first in the form of thyroid
extract, later as inorganic Lugol's solution (iodine plus
potassium iodide) (Gerson, 1958, 32, 409; U.S. Congress, 1946,
114). Several researchers have showed that thyroid raises natural
resistance to infection by augmenting the power of
reticuloendothelial cells and by increasing antibody formation -
thus supporting Gerson's hunch that iodine was a decisive factor
in the normal differentiation of cells (Lurie, 1960; Thorbecke,
1962).
Despite the fact that he had no inpatient facility until 1946,
when he opened a clinic in Nanuet, New York, Gerson managed,
through his thriving Park Avenue practice and an affiliation at
Gotham Hospital, to amass enough data to publish a preliminary
report in 1945. He presented his rather remarkable case histories
modestly, concluding that he did not yet have enough evidence to
say whether diet could either influence the origin of cancer or
alter the course of an established tumor. He claimed only that the
diet, which he described in considerable detail, could favorably
affect the patient's general condition, staving off the
consequences of malignancy and making further treatment possible (Gerson,
1945).
Gerson may have struck an Establishment nerve with his statement
that many physicians use surgery and/or radiation "without
systematic treatment of the patient as a whole" (Gerson, 1945,
419). But it seems more likely that it was his growing success in
practice, or perhaps even his opposition to tobacco, that first
drew the wrath of organized medicine. ( Philip Morris was then
JAMA's major source of advertising revenue: see Rorty, 1939, 182 -
194).
In any case the AMA did not openly attack Gerson until November
1946, a few months after he testified in support of a Senate bill
to appropriate $100 million to bring together the world's
outstanding cancer experts in order to coordinate a search for the
prevention and cure of cancer. At hearings before Senator Claude
Pepper's sub-committee in July 1946, Gerson demonstrated recovered
patients who had come to him after conventional methods could no
longer help. Dr. George Miley, medical director of the 85-bed
Gotham Hospital, where Gerson had treated patients since January,
1946, gave strong supporting medical testimony (U.S. Congress,
1946).
In a surly editorial response, JAMA said it was "fortunate" that
this Senate appearance received little newspaper publicity; the
AMA was clearly outraged that Gerson's appearance had become the
subject of a favorable radio commentary, broadcast nationwide by
ABC's Raymond Gram Swing (U.S. Congress, 1946, 31-35; JAMA, 1946).
The JAMA editorial focused on Gerson, even though it was not
Gerson but a lay witness, immune to AMA retaliation, who had
called Gerson's successes "miracles" and urged the Senators to
secure their future cancer commission against control by any
existing medical organization (U.S. Congress, 1946, 96,97).
It was not Gerson, but Dr. Miley, who told the Senators that a
long-term survey by a well-known and respected physician showed
that those who received no cancer treatment lived longer than
those who received surgery, radiation or X-ray (U.S. Congress,
1946, 117). Perhaps because Miley was a Northwestern medical
graduate, an established physician licensed in four states, and a
fellow of the AMA and state and county societies of Pennsylvania
and New York, Morris Fishbein did not attack him personally.
Instead, he limited himself to intimations of fiscal impropriety
in the Robinson Foundation, which owned Miley's Gotham Hospital,
and to the scandalous revelation that the director of the section
on health education of this Foundation (which was promoting "an
unestablished, somewhat questionable method of treating cancer")
was not an M.D. at all, but a Yale University professor of
economics!
Compared to Miley's testimony, Gerson's was innocent,
concentrating on the histories of the patients he brought with him
and on the likely mechanisms whereby his diet caused tumor
regression and healing. Only under pressure from Senator Pepper
did Gerson state that about 30% of those he treated showed a
favorable response ( U.S. Congress, 1946, 115). Nonetheless, JAMA
devoted two pages to undermining Gerson's integrity (JAMA, 1946).
Showing no restraint where Gerson was concerned, Fishbein,
contrary to fact, alleged that successes with the
Gerson-Sauerbruch-Hermannsdorfer diet "were apparently not
susceptible of duplication by most other observers. " He also
falsely claimed that Gerson had several times refused to supply
the AMA with details of the diet. (Fishbein said he could provide
them in this editorial only because "there has come to hand
through a prospective patient" of Gerson a diet schedule for his
treatment.) Fishbein emphasized, without comment, Gerson's caution
about the use of other medications, especially anesthetics,
because they produced dangerously strong reactions in the
heightened allergic state of his most responsive patients.
Fishbein attempted to tie together this strange patchwork of slurs
against Gerson and against research supported by lay-dominated
industrial corporations with his accustomed mastery of innuendo:
"The entire performance, including the financial backing, the
promotion and the scientific reports, has a peculiar effluvium
which, to say the least, is distasteful and, at its worst, creates
doubt and suspicion" (JAMA, 1946, 646).
Through no fault of his own, Gerson was again portrayed favorably
in the news in 1947, when John Gunther, in Death Be Not Proud,
credited Gerson with extending the life of Gunther's son during
the boy's ultimately unsuccessful struggle with brain cancer.
Beginning that same year the New York County Medical Society
staged five "investigations" of Gerson and eventually suspended
him for "advertising" his "secret" methods.
At this point Gerson's life took on a nightmare quality. The
Pepper-Neely bill met defeat and, with it, the hope for
coordinated cancer research free of prior restraints against
investigations of anything other than "established" methods. In
1949 the AMA Council on Pharmacy and Chemistry, in a report
entitled "Cancer and the Need for Facts", rehashed material from
the earlier editorial, adding that the Gerson diet was "lacking in
essential protein and fat" and that Gerson's concern about the
dangers of anesthesia was "wholly unfounded and apparently
designed to appeal to the cancer victim already fearful of a
surgical operation which might offer the only effective means for
eradication of the disease". Without benefit of either a
literature search or new clinical or laboratory research, the
Council labeled as a "false notion" the idea that "diet has any
specific influence on the origin or progress of cancer". They
concluded that "There is no scientific evidence whatsoever to
indicate that modifications in the dietary intake of food or other
nutritional essentials are of any specific value in the control of
cancer" (Council on Pharmacy and Chemistry, 1949, 96). Gerson lost
his hospital affiliation and found that young doctors who wanted
to assist him and learn from him could not do so, for fear of
incurring Society discipline. He was denied malpractice insurance,
because his therapy was not "accepted practice" (Moss, 1980, 178;
Natenberg, 1959, 136).
In the early fifties Gerson submitted five case histories to the
NCI, requesting an official investigation. He was told that they
would need 25 cases, which he promptly supplied, with full
documentation. More than a year later the NCI demanded 125 case
histories, saying that the 25 they had previously requested were
insufficient to justify investigation.
According to a 1981 publication of the Gerson Institute, headed by
his daughter, Charlotte Gerson, a manuscript for a book he was
writing about his therapy disappeared from his files in 1956
(Healing, 1981, 19) At the age of 75, isolated from medical
colleagues and unable to find assistants, Gerson undertook the
work of rewriting the entire manuscript in order to show "that
there is an effective treatment of cancer, even in advanced cases"
(Gerson, 1958, 3). It was published in 1958, as A Cancer Therapy:
Results of Fifty Cases. Gerson died of pneumonia the following
year, before finishing a second volume. His ideas have gained wide
distribution through subsequent editions of his book (1975, 1977,
and 1986); through a 1962 publication called Has Dr. Max Gerson a
True Cancer Cure?, which had reportedly sold more than 250,000
copies by 1980 (Moss, 1980, 178); and through the publications and
physician-training programs of the Gerson Institute in Bonita,
California, and the Hospital de Baja California.
In 1980 a reformed JAMA carried a commentary called "The 'Grand
Conspiracy' Against the Cancer Cure" by William Regelson of the
Department of Medicine of the Medical College of Virginia.
Surveying a series of "inappropriate judgments [that] have
resulted in injury to good observations," Regelson said, "We may
shortly have to ask if Gerson's low-sodium diet, with its bizarre
coffee enemas and thyroid supplementation, was an approach that
altered the mitotic regulating effect of intracellular sodium for
occasional clinical validity in those patients with the stamina to
survive it" (Regelson, 1980, 338).
Disregarding such suggestions and resting its case instead on the
claim that the NCI had "found no convincing evidence of
effectiveness" during a review of ten Gerson cases some forty
years earlier, the American Cancer Society in 1987 stated that
"The Gerson method of cancer treatment is not considered a proven
means of cancer treatment, and on the basis of available
information, the Institute does not believe that further
evaluation of this therapy is called for at this time" (American
Cancer Society, February 5, 1987).
Testing is underway, however, outside of the U.S. Since 1984 a
modified form of Gerson's therapy has been in use at the Second
Department of Surgery of the Krankenhaus in Graz, Austria.
Omitting liver juice and niacin, using thyroid only in hypothyroid
patients, and limiting caffeine enemas to two per day, Peter
Lechner and his colleagues, all of them surgeons, have been
testing the Gerson method as an adjunct, often with chemotherapy
or radiation, in 60 post-operative cancer patients, male and
female, ranging in age from 23 to 74, and representing many
different forms of cancer. By pairing each patient who was willing
to use the Gerson method (GP) with one of similar age and
condition who chose not to try it (NGP) and observing the
comparative progress of the disease in the two groups over a
four-year period, Lechner and his colleagues have approximated a
controlled study of admittedly imperfect structure (Lechner, 198
7).
Their findings show that the Gerson therapy made a notable
difference in several forms of cancer. Although GPs with bone
metastases had no better survival or tumor response than NGPs,
their relief from pain and absence of hypercalcemia made for a
better quality of life. GPs with lung metastases required fewer
procedures to relieve pleural effusion. GPs with brain metastases
experienced decreased edema and lived four months longer than
their paired NGPs. Premenopausal and perimenopausal breast cancer
GPs tolerated conventional treatments better, with fewer side
effects; showed better liver and kidney function and blood counts;
and had fewer local recurrences and no metastases. Breast cancer
GPs with liver metastases tolerated chemotherapy better, and one
of three has been in a steady state for more than a year, while
the remaining five have died. GPs with colorectal carcinoma seemed
to gain weight and recover better after surgery, but showed no
significant difference in incidence of secondaries or local
recurrence. The best responders to date are GPs with liver
metastases, with two GPs showing improved hepatic enzyme profiles
compared to two NGPs; in four other pairs, although profiles
remained similar, the GPs lived twice as long as the NGPs (Lechner,
1987).
It is an irony of both history and geography that the first
comparative study of Max Gerson's therapy should take place at the
hands of surgeons, in that part of the world which Gerson fled as
a Jewish refugee half a century ago and that the results, while
not so outstanding as those he seemed able to produce, are most
encouraging in patients with severe damage to the liver, the organ
he considered central to recovery.
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